関連する実験動画

Updated: Jul 19, 2026

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
14:27

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity

Published on: August 19, 2013

オクラトキシンaは,炭素結合のc8-デオキシグアノシン核酸アドゥクトを形成する:フェノル系ラジカルによるc8反応性への影響

Jian Dai1, Marcus W Wright, Richard A Manderville

  • 1Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109, USA.

Journal of the American Chemical Society
|March 27, 2003
PubMed
まとめ

発がん性毒素であるオクラトキシンA (OTA) は,デオキシグアノシン (dG) と共性添加物を形成することによって,DNAに直接損傷を与える可能性があります. この発見は,OTAの背後にあるメカニズムを明確にします.

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