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Updated: May 6, 2026

A Plate-based Cytotoxicity Assay for the Assessment of Rat Placental Natural Killer Cell Cytolytic Function
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妊娠前症候群患者のAT1受容体アゴニスティック抗体はNADPH酸化酵素を刺激する

Ralf Dechend1, Christiane Viedt, Dominik N Müller

  • 1HELIOS Klinikum-Berlin, Franz Volhard Clinic and the Max Delbrück Center for Molecular Medicine, Humboldt University of Berlin, Germany.

Circulation
|April 2, 2003
PubMed
まとめ

アンジオテンシンAT1受容体 (AT1-AA) に対するアゴニスティックな自己抗体は,生殖前不妊症において反応性酸素種 (ROS) を増加させ,核因子カッパB (NF-kappaB) を活性化させる. これは,AT1-AAがNADPH酸化酵素活性化による炎症に寄与することを示唆しています.

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