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Updated: Jun 22, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

PAC1フォスファテーゼは,アポトーシスと成長抑制のシグナル伝達においてp53の転写標的である

Yuxin Yin1, Yu-Xin Liu, Yan J Jin

  • 1Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA.

Nature
|April 4, 2003
PubMed
まとめ

腫瘍抑制剤p53は,アポトーシス中にフォスファターゼPAC1 (二重特異性フォスファターゼ2) を活性化させます. PAC1はp53媒介によるアポトーシスと腫瘍抑制に不可欠であり,新しい遺伝子調節機構を明らかにしています.

キーワード:
非プログラム的なものです.

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