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Updated: Jul 11, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
11:33

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes

Published on: March 12, 2013

構成的に活性なアデノシンモノフォスファート活性化タンパク質キナーゼは,心室性ミオサイト内の電圧誘導ナトリウムチャネルを調節する

Peter E Light1, Catriona H R Wallace, Jason R B Dyck

  • 1Department of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. peter.light@ualberta.ca

Circulation
|April 19, 2003
PubMed
まとめ

PRKAG2遺伝子の変異は,致命的な心拍の障害を引き起こす. この研究では,構成的に活性なAMPK (CA-AMPK) がアクションポテンシャル期間を延長し,早期の脱極化を引き起こすことが示され,ナトリウムチャネルがAMPK基質であることを示唆しています.

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