ゲノム革命の潜在力を実現する:生命プログラムへのゲノム
Marvin E Frazier1, Gary M Johnson, David G Thomassen
1U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research, SC-70, Germantown Building, 1000 Independence Avenue, S.W., Washington, DC 20585-1290, USA.
Science (New York, N.Y.)
|April 12, 2003
まとめ
米国エネルギー省は,
科学分野:
- 環境微生物学 環境微生物学
- システム生物学 システム生物学
- ゲノミクスゲノミクスとは
背景:
- システム生物学革命には,様々な分野からの多様な戦略が関わっています.
- 米国エネルギー省 (DOE) は,Genomes to Life (GTL) プログラムを通じてこの問題に取り組んでいます.
- グローバルな環境的課題は,微生物システムの理解における進歩を必要とします.
研究 の 目的:
- 環境微生物生物学を前進させるためのゲノム・トゥ・ライフ (GTL) プログラムの戦略を概説する.
- 数多くの微生物と微生物系の自然生息地に関する基礎的な理解を10~20年以上にわたって確立する.
- 重要な知識,技術,コンピューティング,データ統合のギャップを特定し,対処する.
主な方法:
- グローバルな課題に取り組むために環境微生物生物学に焦点を当てています.
- 微生物システムのための新しい技術とコンピューティングアプローチの開発.
- システムレベルの理解のために,多様なデータと知識を統合する.
主要な成果:
- GTLプログラムは,DOEの戦略的イニシアチブです.
- その目的は,何千もの微生物を,その生息環境で理解することです.
- 重要な課題は,知識,技術,コンピューティング,データ統合にあります.
結論:
- GTLプログラムは,環境微生物生物学を進歩させるために不可欠です.
- 知識と技術のギャップを解決することは,プログラムの目標を達成するために不可欠です.
- 複雑な微生物生態系を理解するには,システムレベルのアプローチが必要である.
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