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Updated: Jul 6, 2026

Murine Superficial Lymph Node Surgery
04:36

Murine Superficial Lymph Node Surgery

Published on: May 21, 2012

CD4 T細胞なしの急性感染症後のCD8 T細胞の欠陥記憶は,CD4 T細胞の助けにならない

Joseph C Sun1, Michael J Bevan

  • 1Department of Immunology and the Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|April 12, 2003
PubMed
まとめ

CD4+ヘルパーT細胞は,長期にわたるCD8+細胞毒性T細胞記憶の形成に不可欠である. 初期感染に対するCD8+T細胞の反応は,CD4+の助けがなければ正常であるが,保護記憶は損なわれ,二次反応に影響する.

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Overview
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T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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T Cell Types and Functions

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Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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