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Updated: Jul 16, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

IKKに関連する経路を通じてインターフェロンの抗ウイルス反応を誘発する

Sonia Sharma1, Benjamin R tenOever, Nathalie Grandvaux

  • 1Lady Davis Institute for Medical Research-Jewish General Hospital, Departments of Microbiology and Immunology and Medicine, McGill University, Montreal, Quebec H3T 1E2, Canada.

Science (New York, N.Y.)
|April 19, 2003
PubMed
まとめ

この研究は,イカッパBキナーゼ (IKK) 関連キナーゼを,インターフェロン調節因子 (IRF) 3および7の主要な活性化剤として特定しています. この発見は,ウイルス感染症に対する宿主抗ウイルス反応の重要なステップを明らかにします.

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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

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