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Updated: May 24, 2026

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
10:16

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

Published on: June 28, 2018

アルファヘリックス媒介のタンパク質相互作用を標的とする遺伝子発現阻害剤

Shinichi Asada1, Yongmun Choi, Motonari Uesugi

  • 1The Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

Journal of the American Chemical Society
|April 24, 2003
PubMed
まとめ

研究者らは,タンパク質の相互作用を妨害することによって,Her2腫瘍遺伝子の発現を抑制する新しい有機分子であるアダマノロールを発見しました. この化合物は,ヘル2陽性乳がん細胞を選択的に殺し,新たな治療法を提供している.

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