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Updated: Jul 22, 2026

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

核酸塩基対ダイナミクス:自由エネルギー計算を用いた配列と構造の影響

Emmanuel Giudice1, Richard Lavery

  • 1Laboratoire de Biochimie Théorique, CNRS UPR 9080, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, Paris 75005, France.

Journal of the American Chemical Society
|April 24, 2003
PubMed
まとめ

A-トラクトは,A-RNA構造の変化に対するB-DNAの軽微な影響とは異なり,DNA塩基対の寿命を大幅に延長します. 分子ダイナミクスシミュレーションは,核酸のこれらの異なる行動の背後にある理由を明らかにします.

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