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Updated: Jul 6, 2026

Reconstitution of Membrane-Tethered Minimal Actin Cortices on Supported Lipid Bilayers
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トランスメブランヘリックス結合の調節によるインテグリンαIIbbeta3の活性化

Renhao Li1, Neal Mitra, Holly Gratkowski

  • 1Department of Biochemistry and Biophysics, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|May 6, 2003
PubMed
まとめ

インテグリントランスメブランヘリックス変異は,インテグリンαIIbbeta3の活性化とクラスタリングを促進します. トランスメブランドメインのホモメール結合がインテグリン活性を促進し,活性化とクラスタリングの構造的基盤を提供します.

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