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Updated: May 5, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

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アクチンダイナミクスは,同活性化剤MALの調節により,SRFの活動を制御する

Francesc Miralles1, Guido Posern, Alexia-Ileana Zaromytidou

  • 1Transcription Laboratory, Room 401, Cancer Research UK London Research Institute, Lincolns Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Cell
|May 7, 2003
PubMed
まとめ

RhoGTPaseは,アクチンポリメリゼーションを調節することによって,転写因子SRFを制御する. この研究は,Rho-actinシグナル伝達が,SRFの活性化のための重要なメカニズムであるSRF共活性化剤MALの核の局所化を指示することを明らかにしています.

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