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Updated: May 12, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

グローバル・コントロール・リージョンは,ホックスDクラスタを含む染色体調節ランドスケープを定義します

François Spitz1, Federico Gonzalez, Denis Duboule

  • 1Department of Zoology and Animal Biology, NCCR Frontiers in Genetics, University of Geneva, Sciences III, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland.

Cell
|May 7, 2003
PubMed
まとめ

研究者らは,四肢の発達中にホックスド遺伝子発現を制御する保存されたDNA領域を特定しました. この領域は大きな調節領域として作用し,複数の遺伝子に影響を与え,Ulnaless変異によって破壊されます.

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Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

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An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations11:36

An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations

Published on: April 21, 2023

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