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Updated: May 5, 2026

Invasion of Human Cells by a Bacterial Pathogen
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Published on: March 21, 2011

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病原性バクテリアは,タンデムベータジッパーを通してヒトフィブロネクチンに結合します

Ulrich Schwarz-Linek1, Jörn M Werner, Andrew R Pickford

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Nature
|May 9, 2003
PubMed
まとめ

Staphylococcus aureusやStreptococcus pyogenesのような細菌病原菌は,フィブロネクチン結合タンパク質 (FnBPs) を使用して宿主細胞に侵入します. この研究は,これらの細菌のFnBPsが,フィブロネクチンモジュールを結合するためにタンデムベータ-ジッパーを形成し,重要な侵入機構を説明する方法を明らかにしています.

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