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Updated: Jul 16, 2026

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
13:40

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa

Published on: February 17, 2014

AcrB マルチドラッグ 流出ポンプの複数の薬物結合能力の構造的基礎

Edward W Yu1, Gerry McDermott, Helen I Zgurskaya

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.

Science (New York, N.Y.)
|May 10, 2003
PubMed
まとめ

AcrBのような多剤流出ポンプは,がんや細菌感染症の治療をターゲットにすることができます. 新しい構造は,複数の薬物分子がポンプ内で結合する方法を明らかにし,薬物設計の洞察を提供します.

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Characterizing Multidrug Efflux Systems in Acinetobacter baumannii Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System05:06

Characterizing Multidrug Efflux Systems in Acinetobacter baumannii Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

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