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Updated: Jul 5, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

小型GTPase Rab6に対する再結合抗体は,コンフォームセンサとして使用されます

Clement Nizak1, Solange Monier, Elaine del Nery

  • 1CNRS UMR144, Institut Curie, 26 rue d'Ulm, F75248 Paris Cedex 05, France.

Science (New York, N.Y.)
|May 10, 2003
PubMed
まとめ

研究者らは,抗体ファグディスプレイを用いた分子構成センサを開発し,グアノシントリフォスファターゼ (GTPase) Rab6.6を追跡した. この方法は,細胞内のRab6-GTPを可視化し,輸送中介物質の調節におけるその役割を明らかにし,分子ダイナミクスを研究するための新しいツールを提供します.

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