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Updated: Apr 30, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

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酸化ストレス中の内皮細胞生存におけるL-アルギニンの重要な役割

Christoph V Suschek1, Oliver Schnorr, Karsten Hemmrich

  • 1Research Group Immunobiology, Geb.: 23.12.02, Heinrich-Heine-University Duesseldorf, PO Box 10 10 07, D-40001 Duesseldorf, Germany. suschek@uni-duesseldorf.de

Circulation
|May 14, 2003
PubMed
まとめ

生理学的アルギニンレベルは,内皮誘導性酸化窒素合成酵素 (iNOS) の活性を低下させ,酸化ストレスと内皮機能障害に対する感受性を高めます. アルギニンの濃度を低下させると,動脈硬化症の発症のリスクが著しく高まります.

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