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Updated: May 12, 2026

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3代目のベータブロッカーは,ATP流出を通じて内皮細胞から酸化窒素の放出を刺激する:抗高血圧作用のための新しいメカニズム

Leszek Kalinowski1, Lawrence W Dobrucki, Miroslawa Szczepanska-Konkel

  • 1Department of Chemistry and Biochemistry, Ohio University, Athens, Ohio 45701, USA.

Circulation
|May 14, 2003
PubMed
まとめ

ネビボロールとカルベディロールは,酸化窒素 (NO) の放出を刺激することによって,血管のリラックスを促進します. これは,微血管内皮細胞における細胞外アデノシン三リン酸 (ATP) とP2Y-ピューリノセプターの活性化によって発生する.

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