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関連する概念動画

Membrane Fluidity01:26

Membrane Fluidity

14.0K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
14.0K
Mechanisms of Membrane-bending01:15

Mechanisms of Membrane-bending

2.6K
The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
2.6K
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

1.9K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
1.9K
Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

9.6K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
9.6K
Fascicle Arrangement in Skeletal Muscles01:25

Fascicle Arrangement in Skeletal Muscles

5.0K
Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
The four primary types of muscle based on fascicle arrangement are:
5.0K
Equilibrium and Balance01:15

Equilibrium and Balance

6.2K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
6.2K

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関連する実験動画

Updated: May 1, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes
07:49

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

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繰り返されるバランスのとれた皮質活動をオン・オフする.

Yousheng Shu1, Andrea Hasenstaub, David A McCormick

  • 1Department of Neurobiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, USA.

Nature
|May 16, 2003
PubMed
まとめ

局所的な皮質回路は,興奮と抑制のバランスを保ち,安定した,自立した神経活動を生み出します. この発見は,脳機能における再発性ネットワークの重要な役割を果たしていることを確認しています.

科学分野:

  • 神経科学は神経科学である.
  • 計算神経科学とは

背景:

  • 大脳皮質は主に刺激神経と抑制神経細胞によって形成された局所および遠隔の再発性ネットワークを使用します.
  • 理論的なモデルは,安定した活動のために,これらのネットワークにおける刺激と抑制のバランスを予測しています.

研究 の 目的:

  • 局所皮質回路の動作原理を調査する.
  • 繰り返される興奮と阻害が皮質ネットワークで比例的にバランスを取っているかどうかを判断する.
  • 局所的な皮質回路における自給自足活動の発生を調査する.

主な方法:

  • 局所的な皮質回路の実験的調査.
  • シナプス結合とニューロン活動の分析.
  • 繰り返しのネットワークダイナミクスのモデリング.

主要な成果:

  • 局所的な皮質回路は,再発的な興奮と抑制の間の比例的なバランスを示しています.
  • このバランスは,安定した,自立した神経活動の生成を可能にします.
  • シナプス入力が,この活動の開始と停止を制御することが示されました.

結論:

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Author Spotlight: Photo Switchable Protein Recruitment for Reversible Patterning in Artificial Cellular Systems

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関連する実験動画

Last Updated: May 1, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes
07:49

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

4.8K
Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients
09:17

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients

Published on: May 17, 2020

3.4K
Author Spotlight: Photo Switchable Protein Recruitment for Reversible Patterning in Artificial Cellular Systems
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Author Spotlight: Photo Switchable Protein Recruitment for Reversible Patterning in Artificial Cellular Systems

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  • 局所的な再発性皮質回路は,バランスのとれた興奮抑制メカニズムで動作します.
  • このバランスの取れた活動は,記憶や注意力などの基本的な脳機能をサポートします.
  • この研究は,皮質機能における再発性活動の役割に関する長年の仮説を検証しています.