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Differentiation and Characterization of Osteoclasts from Human Induced Pluripotent Stem Cells
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オステオクラストの分化と活性化

William J Boyle1, W Scott Simonet, David L Lacey

  • 1Protein Pathways, Inc., Woodland Hills, California 91367, USA. bboyle@proteinpathways.com

Nature
|May 16, 2003
PubMed
まとめ

骨の再構築に不可欠な骨格クラストは,骨マトリックスを劣化させます. RANKシグナル伝達経路は,オステオクラストの機能と,骨粗鬆症のような骨粗鬆症の潜在的な治療法についての洞察を提供します.

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