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Bacterial Phylum Spirochaetes
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B細胞前急性リンパ性白血病におけるアダプタSLP-65の欠乏症

Hassan Jumaa1, Lukas Bossaller, Karina Portugal

  • 1Biologie III, University of Freiburg and Max Planck Institute for Immunobiology, D-79108 Freiburg, Germany. jumaa@immunbio.mpg.de

Nature
|May 23, 2003
PubMed
まとめ

アダプタタンパク質SLP-65 (BLNKとも呼ばれる) は,マウスにおけるB細胞前白血病を予防します. SLP-65発現の喪失は,ヒトの小児期の急性リンパ性白血病で観察され,この悪性腫瘍を引き起こす可能性があることを示唆しています.

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