関連する実験動画

Updated: Jul 18, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

構造と選択性を相関させる量子力学モデル:アルデヒドアルキレーションにおけるβ-アミノアルコール触媒のエナチオ選択性を予測する

Marisa C Kozlowski1, Steven L Dixon, Manoranjan Panda

  • 1Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, PA 19104-6323, USA. marisa@sas.upenn.edu

Journal of the American Chemical Society
|May 29, 2003
PubMed
まとめ

定量構造選択性関係 (QSSR) モデルは,非対称な触媒におけるエナチオ選択性を予測する. これらのモデルは,単純な理論的計算と実験データを使用して,信頼性と迅速な予測を提供します.

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Induced-fit Model01:13

Induced-fit Model

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Enzymes02:34

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Introduction to Mechanisms of Enzyme Catalysis

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Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes a mild...
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Heterogeneous Catalysis

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