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Updated: Jul 8, 2026

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
11:25

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins

Published on: October 4, 2017

改良されたリボソームによってタンパク質にD-アミノ酸の組み込みが強化された

Larisa M Dedkova1, Nour Eddine Fahmi, Serguei Y Golovine

  • 1Departments of Chemistry and Biology, University of Virginia, Charlottesville, VA 22904, USA.

Journal of the American Chemical Society
|May 29, 2003
PubMed
まとめ

改変されたEscherichia coliのリボソームにより,D-アミノ酸がタンパク質に組み込まれることが可能になる. ディヒドロフォラート還元酵素のような,結果として生成されたいくつかのタンパク質は,完全な機能を保持し,新しいタンパク質工学の可能性を実証しました.

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