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関連する概念動画

Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...

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関連する実験動画

Updated: Jul 6, 2026

Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering
11:32

Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering

Published on: December 20, 2010

心肺バイパスにおけるコルチゾール反応

K M Taylor, J V Jones, M S Walker

    Circulation
    |July 1, 1976
    PubMed
    まとめ

    心肺バイパスによる心臓外科手術は,コルチゾール反応を変化させ,バイパス中にレベルが低く,対照群と比較して手術後のレベルが上昇します. ACTHに対する腎上腺の反応はバイパス中に保存されます.

    科学分野:

    • エンドクリノロジー エンドクリノロジー
    • 心血管外科手術についてです.
    • 生理学 生理学とは

    背景:

    • 心肺バイパスによる心臓外科手術は,重要な生理学的ストレス因子です.
    • 内分泌の反応,特にコルチゾールの理解は,患者の管理に不可欠です.

    研究 の 目的:

    • 心肺バイパスによる心臓手術を受ける患者のプラズマコルチゾールとプラズマフリーコルチゾール反応パターンを調査する.
    • これらのパターンを閉じたミトラバルボトミーを受けた対照患者と比較するために.

    主な方法:

    • 心肺バイパスによる心臓手術を受けた20人の患者と,閉じたミトラバルボトミーを受けた16人の対照患者について研究した.
    • 血の全コルチゾールと血のフリーコルチゾールのレベルを様々な時間点で測定した.
    • 手術中に合成ACTH刺激を用いた副腎皮質の反応を評価した.

    主要な成果:

    • バイパス患者の体外循環 (ECC) 中の血コルチゾールの総量は,典型的なストレス反応を示した対照群とは異なり,減少した.
    • コルチゾール濃度の上昇は,バイパス手術患者の手術後24~48時間持続した.
    • ACTHに対する腎上腺反応はバイパス中に無傷だったが,手術中のコントロールでは無かった.

    さらに関連する動画

    Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
    10:05

    Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

    Published on: July 7, 2016

    Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
    07:20

    Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model

    Published on: February 10, 2023

    関連する実験動画

    Last Updated: Jul 6, 2026

    Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering
    11:32

    Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering

    Published on: December 20, 2010

    Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
    10:05

    Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

    Published on: July 7, 2016

    Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
    07:20

    Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model

    Published on: February 10, 2023

  • ECCの発症時にフリーコルチゾールの割合は上昇したが,バイパス患者のECC中にプラズマフリーコルチゾールの総量は低下した.
  • 術後のプラズマフリーコルチゾールはバイパス手術を受けた患者で有意に高かった.
  • 結論:

    • 心肺バイパスは,正常なコルチゾールのストレス反応パターンを大幅に変化させます.
    • 副腎皮質は,心肺バイパス中にACTHに対する反応性を維持します.
    • 手術後のコルチゾールのレベルは,心臓肺バイパス手術を受けた患者で上昇しています.