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Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed protons being...
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Heterokaryon Technique for Analysis of Cell Type-specific Localization
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Published on: March 11, 2011

あるポリモルフが別のポリモルフによって核化される.

Lian Yu1

  • 1Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA. yu_lian@lilly.com

Journal of the American Chemical Society
|June 6, 2003
PubMed
まとめ

一つのポリモルフは,d-マニトールとd-ソルビトールの溶融結晶化中に直接別のポリモルフを誘導した. この発見は,化学製造を制御し,ポリモルフな核化を理解するための鍵となるものである.

科学分野:

  • マテリアルサイエンス 材料科学
  • 化学工学は化学工学というものです.
  • クリスタルグラフィーです.

背景:

  • ポリモルフィズム,つまり固体の物質が複数の結晶形に存在する能力は,化学製品の特性や製造プロセスに大きな影響を与えます.
  • ポリモルフィズムを制御することは,特殊化学品,医薬品,および材料科学にとって不可欠ですが,相変換を予測し制御することは依然として困難です.
  • 現在の研究は,新しいポリモルフが親相から自発的に形成される同質な核形成に焦点を当てていることが多い.

研究 の 目的:

  • 溶融結晶の過程で,あるポリモルフが別のポリモルフによって異質な核形成を直接観察し,記録する.
  • 1つの結晶形が,d-マニトールとd-ソルビトールの異なるポリモルフの核形成と成長を誘導する現象を調査する.
  • ポリモルフィズムを制御し,同時に発生するポリモルフ形成を理解するための洞察を提供する.

主な方法:

  • 溶融結晶化実験は,d-マニトールとd-ソルビトールで実施されました.
  • 核形成と成長プロセスを監視するために,直接的な観察技術が採用されました.
  • 分析は,初期核形成ポリモルフと,その結果生じる支配的ポリモルフを特定することに焦点を当てました.

主要な成果:

  • あるポリモルフが既存のポリモルフに核を形成している直接的な証拠は,溶融結晶化中に得られた.

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関連する実験動画

Last Updated: Jul 20, 2026

Heterokaryon Technique for Analysis of Cell Type-specific Localization
09:31

Heterokaryon Technique for Analysis of Cell Type-specific Localization

Published on: March 11, 2011

A Modified Yeast-one Hybrid System for Heteromeric Protein Complex-DNA Interaction Studies
10:47

A Modified Yeast-one Hybrid System for Heteromeric Protein Complex-DNA Interaction Studies

Published on: July 24, 2017

Synthesis of Single-Crystalline Core-Shell Metal-Organic Frameworks
05:26

Synthesis of Single-Crystalline Core-Shell Metal-Organic Frameworks

Published on: February 10, 2023

  • 新しく核化したポリモルフは成功裏に成長し,最終製品における支配的な結晶形になりました.
  • これは,既存の結晶構造が新しい結晶構造の形成をテンプレート化した異質な核形成経路を示しています.

    • 結論:

    • 一つのポリモルフが別のポリモルフを誘導する異質な核化は,d-マニトールとd-ソービトールの溶融結晶化の重要な要因です.
    • この現象は,工業化学製造におけるポリモルフィズムを制御するための実用的な経路を提供します.
    • この発見は,ポリモルフな核形成と同時に発生するポリモルフの理論的理解を深めるのに寄与する.