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Updated: Jul 9, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

NF-kappaB依存遺伝子発現におけるIkappaBキナーゼアルファの核細胞機能

Vasiliki Anest1, Julie L Hanson, Patricia C Cogswell

  • 1Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

Nature
|June 6, 2003
PubMed
まとめ

核IKK-αは,ヒストンH3.3をリン酸化することによってNF-kappaB遺伝子発現を調節する. この発見は,サイトカイン媒介の細胞応答におけるIKK-αの新たな役割を明らかにしています.

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