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関連する概念動画

Glycolysis: Pay-off Phase01:25

Glycolysis: Pay-off Phase

So far, glycolysis has cost the cell two ATP molecules and produced two small, three-carbon sugar molecules. These molecules will proceed through the second half of the pathway, and sufficient energy will be extracted to pay back the two ATP molecules used as an initial investment and produce a profit for the cell of two additional ATP molecules and two even higher-energy NADH molecules.
Step 1 - 5: Glycolysis Preparatory Phase
The first phase of glycolysis has 5 steps where the glucose is...
Cardiac Cycle01:29

Cardiac Cycle

The cardiac cycle refers to the sequence of events that occur in the heart from the beginning of one heartbeat to the next. It's characterized by alternating periods of contraction (systole) and relaxation (diastole) of the heart muscles.
During the cardiac cycle, blood flow through the heart is regulated entirely by changing pressure gradients. This sequence of events begins with the heart in a state of total relaxation, known as mid-to-late diastole, during which blood passively flows from...
Conservation of Mass in Finite Cotrol Volume01:16

Conservation of Mass in Finite Cotrol Volume

The principle of conservation of mass is a fundamental law in fluid mechanics and is applied using the continuity equation. We apply the concept to a finite control volume to derive the continuity equation.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.
Steady, Laminar Flow in Circular Tubes01:23

Steady, Laminar Flow in Circular Tubes

Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is purely axial,...
Area Problem01:26

Area Problem

Determining the area of a region with straight edges is straightforward, as geometric formulas for rectangles, triangles, and polygons can be applied directly. However, traditional geometric methods are insufficient when a region has a curved boundary, such as the area under a function.fromThe area problem involves finding a systematic way to measure such regions. One approach to solving this problem is through approximation. Instead of attempting to compute the area exactly at the outset, the...
Green’s Theorem01:27

Green’s Theorem

Green’s Theorem establishes a relationship between a line integral around a closed plane curve and a double integral over the region enclosed by that curve. It applies to a vector field F(x, y) = 〈P(x, y), Q(x, y)〉, where P and Q have continuous first partial derivatives on an open set containing the region.Let C be a positively oriented, simple, closed, piecewise smooth curve, and let R be the plane region bounded by C. Green’s Theorem states that\begin{equation*}\oint_C P\,dx+Q\,dy =\iint_R...

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関連する実験動画

Updated: Jul 17, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180&#176; Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

シルカディアンリズム:ついにループに入りました.

Russell N Van Gelder1, Erik D Herzog, William J Schwartz

  • 1Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO 63110, USA. vangelder@vision.wustl.edu

Science (New York, N.Y.)
|June 7, 2003
PubMed
まとめ

動物の昼夜時計は,似たような分子フィードバックループを使用しているが,哺乳類と果物ハエでは異なる遺伝子を採用している. この比較は,生物学的時間測定における保存された原理と異なる分子プレーヤーを強調しています.

科学分野:

  • クロノバイオロジー クロノバイオロジー
  • 分子生物学は分子生物学である.
  • 比較ゲノミクスとは

背景:

  • シルカディアンオシレータは,種を超えて保存されている基本的な生物学的プロセスです.
  • これらの振動器は,通常,時計遺伝子製品を含む負のフィードバックループに依存します.
  • 動物の昼間時計は,強固な振動のために少なくとも2つの相互作用するフィードバックループを統合しています.

研究 の 目的:

  • 哺乳類とドロソフィラの昼夜時計の分子機構を比較して対比する.
  • 異なる分子プレーヤーが保存された昼夜調節スクリプトを実行する方法を解明する.
  • 生物の時間計測システムにおける進化の分岐と収束を強調する.

主な方法:

  • 既知の哺乳類とドロソフィラの昼間時計遺伝子経路の比較分析.
  • 分子成分と相互作用に関する既存の文献のレビュー.
  • 科学の信号伝達知識環境のリソースを利用する.

主要な成果:

  • 哺乳類とドロソフィラは,日中リズムを生成するために振動するフィードバックループを使用しています.
  • 共通の基本スクリプトにもかかわらず,異なる遺伝子とタンパク質のセットが各グループでこれらのループを形成します.

さらに関連する動画

Evolution of Staircase Structures in Diffusive Convection
07:28

Evolution of Staircase Structures in Diffusive Convection

Published on: September 5, 2018

Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation
11:41

Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation

Published on: February 1, 2020

関連する実験動画

Last Updated: Jul 17, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180&#176; Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

Evolution of Staircase Structures in Diffusive Convection
07:28

Evolution of Staircase Structures in Diffusive Convection

Published on: September 5, 2018

Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation
11:41

Evaluation of an Exclusive Spur Dike U-Turn Design with Radar-Collected Data and Simulation

Published on: February 1, 2020

  • 重要な違いは,負のフィードバックメカニズムを駆動する特定の分子プレーヤーに存在します.
  • 結論:

    • シルカディアン・タイムキーピングの基本的原理は,様々な動物の分類にわたって保存されています.
    • 進化は,保存された昼夜機能を実装するために,異なる分子溶液を形作っています.
    • これらの比較経路を理解することで,生物学的時計の強さと適応性についての洞察が得られます.