関連する実験動画

Updated: Jul 6, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

RPA-ssDNA複合体のATRIP認識を通じてDNA損傷を感知する

Lee Zou1, Stephen J Elledge

  • 1Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|June 7, 2003
PubMed
まとめ

複製タンパク質A (RPA) は,ATR-ATRIP複合体をDNA損傷部位に誘導し,重要な細胞チェックポイントシグナル伝達経路を開始するために不可欠です. この発見は,RPAを強調しています.

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Analyzing DNA-Protein Interactions with Streptavidin-Based Biolayer Interferometry

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