関連する実験動画

Updated: Jul 14, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

トリプレックスセレクティブ2・...2・ナフチル・キノリン化合物:親和性の起源と新しい設計原理

Jonathan B Chaires1, Jinsong Ren, Maged Henary

  • 1Department of Biochemistry, University of Mississippi Medical Center, 2500 N. State Street, Jackson, Mississippi 39216-4505, USA. jchaires@biochem.umsmed.edu

Journal of the American Chemical Society
|June 12, 2003
PubMed
まとめ

研究者は,トリプルックスDNAを標的とした新しい化合物を開発し,特定のトリプルックス構造に対する高い選択性を示しました. 定量的構造-親和関係は,より効果的なトリプルックス結合剤の設計を導く.

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Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

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