適応的進化は,ドロソフィラの2つの種間のハイブリッド不活性性の遺伝子の分岐を促します
Daven C Presgraves1, Lakshmi Balagopalan, Susan M Abmayr
1Department of Biology, University of Rochester, Rochester, New York 14627, USA. dvnp@mail.rochester.edu
Nature
|June 13, 2003
まとめ
種の進化における生殖的孤立は,ハイブリッドの生命不全を引き起こす可能性があります. 核毛孔タンパク質遺伝子は,陽性選択によって進化し,適応の副産物として致命的なハイブリッド不適合性をもたらしました.
科学分野:
- 進化生物学の進化生物学について
- 遺伝学 遺伝学とは
- 専門分野の研究は,専門分野の研究である.
背景:
- 種種化は生殖的孤立を伴うもので,ハイブリッドの不妊または無生命性につながる.
- ハイブリッドの不適合性は,しばしば遺伝的位置間の不適合な相互作用から生じます.
- これらの不適合性の特定の遺伝子と進化的要因は,ほとんど不明のままである.
研究 の 目的:
- 致死性のハイブリッドの相容れない遺伝子を特定する.
- これらの遺伝子の分岐を促す進化的力を調査する.
主な方法:
- 集団遺伝分析 集団遺伝分析
- 比較ゲノミクスとは
- 候補遺伝子の機能分析
主要な成果:
- 核毛孔タンパク質をコードする特定の遺伝子を特定し,Drosophila melanogasterとD. simulansのハイブリッドにおいて,エピスタティック不活性を引き起こした.
- 集団遺伝分析は,この遺伝子が両方の種において,陽性な自然選択の下で進化したことを示した.
- 致死性のハイブリッドの不相容性が,適応性タンパク質の進化によって生じたことを実証した.
結論:
- 適応性タンパク質の進化は,致命的なハイブリッド不適合性を生み出すことができます.
- 核孔タンパク質は,種化プロセスに関与しています.
- 相互作用する遺伝子のポジティブ・セレクションは,生殖的孤立を促すことができる.
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