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Updated: Jul 10, 2026

Measuring In Vitro ATPase Activity for Enzymatic Characterization
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Measuring In Vitro ATPase Activity for Enzymatic Characterization

Published on: August 23, 2016

タンパク質チロシンフォスファタゼ1Bの活性部位システインの酸化状態

Rob L M van Montfort1, Miles Congreve, Dominic Tisi

  • 1Astex Technology Ltd, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK.

Nature
|June 13, 2003
PubMed
まとめ

酸化ストレスは,タンパク質チロシンファスファテーゼ1B (PTP1B) に不可逆的に損傷を与える可能性があります. 研究者らは,PTP1Bの損傷を防止し,その再活性化に役立つ保護性スルフェニルアミド中間物質を発見した.

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