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Updated: Jul 19, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
04:48

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate

Published on: July 10, 2018

長期にわたる小脳うつ病に対するAMPA受容体GluR2リン酸化の必要性

Hee Jung Chung1, Jordan P Steinberg, Richard L Huganir

  • 1Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205 USA.

Science (New York, N.Y.)
|June 14, 2003
PubMed
まとめ

シナプス記憶の一形態である脳小球長期抑うつ症 (LTD) は,シナプス後のAMPA受容体を減少させるためにタンパク質キナーゼC (PKC) に依存しています. Ser880におけるGluR2のPKCリン酸化は,小脳LTDを誘発するために不可欠である.

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