インスリン受容体基板-2の欠如は,血管損傷への反応として進行的なネオインティマ形成を引き起こす

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Updated: Jul 5, 2026

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
09:41

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery

Published on: December 23, 2014

Tetsuya Kubota1, Naoto Kubota, Masao Moroi

  • 1Third Department of Internal Medicine, Toho University School of Medicine, Ohashi Hospital 2-17-6 Ohashi, Meguro-ku, Tokyo 153-8515, Japan.

Circulation
|June 18, 2003
PubMed
まとめ

インスリン受容体基板-2 (IRS-2) の欠乏は,インスリン抵抗性マウスのネオインティマ形成を悪化させ,IRS-2が代謝疾患における血管損傷から保護することを示唆しています. IRS-2欠乏症は,血管損傷に対する感受性を高めます.

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