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Updated: Jul 11, 2026

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Published on: July 17, 2020

グリコシル・フォスファディチル・イノシトール 組織因子経路阻害剤の固定

Jing Zhang1, Orlando Piro, Lan Lu

  • 1Division of Hematology, Barnes-Jewish Hospital at Washington University Medical Center, St Louis, Mo, USA.

Circulation
|July 2, 2003
PubMed
まとめ

内皮細胞の組織因子経路阻害剤 (TFPI) は,グリコシルフォスファティディルニノシトール (GPI) と他のタンパク質を介して固定されます. この膜結合は,局所的に凝固を調節するために極めて重要です.

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