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Updated: Jul 7, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

ポリアミド−インターカレーター結合体によるタンパク質−DNA複合体のアロステリック抑制

Eric J Fechter1, Peter B Dervan

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|July 10, 2003
PubMed
まとめ

新しいヘアピンポリアミド-アクリジン結合体は,タンパク質-DNAの相互作用を阻害することによって,遺伝子転写を阻害します. これらの分子はDNAに特異的に結合し,その構造を変化させ,転写因子の結合を防ぐ.

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