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Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
左心室内静脈機能に対する前頭部ミトラ小葉片二次性ホルデ・テンディネアの影響
Sten Lyager Nielsen1, Tomasz A Timek, G Randall Green
1Department of Cardiothoracic and Vascular Surgery and Institute of Experimental Clinical Research, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark.
Circulation
|July 16, 2003
まとめ
羊の前側筋切断は,挿入部位近くの左心室 (LV) のシストリック機能を急激に低下させた. これは,中傷した心室におけるミトラル反吐のための切断の手続きの潜在的なリスクを強調しています.
科学分野:
- 心血管生理学 心血管の生理学
- 心臓のメカニズム 心臓のメカニズム
- 外科技術革新は,外科技術革新である.
背景:
- 左心室 (LV) 収縮力学における前頭部ミトラル小葉片二次性コルデ・テンディネエの役割は,依然として議論されている.
- この貢献を理解することは,心臓病に対する効果的な治療法の開発に不可欠です.
研究 の 目的:
- 前側動脈 (ACT) と後側動脈 (PCT) が,地域および世界的なLV収縮機能に与えるインビボの貢献度を定量化する.
- これらのコーデーを切断することで,LVメカニズムに及ぼす急性効果を評価する.
主な方法:
- ラジオパークマーカーは,羊のLVエピカルディウムに埋め込まれ,12つの領域を定義しました.
- マイクロミニチュアフォーストランスデューサは,ACTとPCTでコードの緊張を測定しました.
- 血液動力学データと地域機能 (断片面縮小,r-PRSW) は,コルダ切断 (CUT) の前後に記録された.
主要な成果:
- グローバルLVシストリック機能は,CUT後の影響を受けませんでした.
- 断片面縮小 (FAS) は,PCT挿入部位付近のLVセグメントで減少した.
- 地域PRSW (r-PRSW) はACTとPCTの両方の挿入場所の近くで著しく減少しました.
- 後部動脈 (PCT) は前部動脈 (ACT) よりも高い最大張力を示した.
結論:
- 前部レフレット・ストート・コルダの急性分裂は,帯状挿入部位における地域的なLVの縮機能不全を引き起こした.
- 二次性ホルダの切断を伴う手順は,特に既にある障害のある心室では注意が必要です.
- これらの発見は,このような介入の後,LVシストリック機能の潜在的な妥協を示唆しています.
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