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Quantitative Autonomic Testing
Published on: July 19, 2011
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血圧と心拍数変動の間の相変化の変動性:短期的な循環制御のマーカー
Josef Halámek1, Tomás Kára, Pavel Jurák
1Institute of Scientific Instruments, Academy of Sciences, Královopolská 147, 612 64 Brno, Czech Republic. josef@isibrno.cz
Circulation
|July 16, 2003
まとめ
0.10 Hzで制御された呼吸は,血圧と心拍の相互作用の違いを明らかにします. これらの発見は,特にカーディオバーター-除細動器受容者において,突然の心臓死のリスクの階層化に役立ちます.
科学分野:
- 心血管の生理学 心血管の生理学
- 自律神経系の機能は,自律神経系の機能である.
- 医療診断 医療診断
背景:
- 循環器の自律的制御は,心臓血管の健康にとって極めて重要です.
- 血圧と心拍数の変動の変動は,自律的機能不全を示唆する可能性があります.
- 0.10 Hzの周波数は,これらの変動を評価する際の潜在能力を探求しています.
研究 の 目的:
- 血圧と心拍数変動の間の相変化変動の有用性を調査するために,自律的循環制御を評価するために0.10Hz近くの血圧と心拍数変動.
- これらの測定を用いて,健康な個人と心血管疾患の患者の区別を図る.
- これらの違いを明らかにするための最適の制御呼吸頻度を決定する.
主な方法:
- 4つの被験者グループが研究されました:健康な若者,健康な高齢者,冠動脈疾患の患者,および心動除細動器 (ICD) 受容者.
- データは,自由呼吸と0.10Hzと0.33Hzで制御された呼吸の間に収集されました.
- 分析は,相変化の変動性とバロレフレクスの感度に焦点を当てた.
主要な成果:
- ICD受容者と他のすべてのグループ間で相変動の有意な差異 (P<0.001) が観察されました.
- 0.10 Hzでは,0.33 Hzとは異なり,バロレフレクスの感受性における有意な差異 (P<0.01) が明らかでした.
- 健康な若者と高齢者は,バロレフレクスの増幅では異なっていたが,相変動はそうではなかった.
結論:
- 0.10 Hzの制御呼吸頻度は,血圧とRRの相互作用を特定するのに有効です.
- これらの相互作用は,相の変動性とバロレフレクスの感受性によって測定され,突然の不律性死のリスクのある患者では有意に変化します.
- これらの短期循環制御測定は,突然の心臓死のリスクの階層化を改善する可能性があります.
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