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Updated: Jul 19, 2026

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ラモプラニンは,リピドIIにダイマーとして結合することによって,細菌のトランスグリコシラゼを阻害する

Yanan Hu1, Jeremiah S Helm, Lan Chen

  • 1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.

Journal of the American Chemical Society
|July 17, 2003
PubMed
まとめ

抗生物質であるラモプラニンは,リピドIIに結合することで,細菌のトランスグリコシラゼを抑制する. この結合はダイマーとして発生し,その強力な抗菌活性を説明します.

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