MyD88から独立したTIR信号のキートランスデューサーとしてのLps2の識別

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Updated: May 9, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

K Hoebe1, X Du, P Georgel

  • 1Department of Immunology, IMM-31, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Nature
|July 23, 2003
PubMed
まとめ

研究者らは,トール/インターリューキン-1受容体/抵抗 (TIR) アダプタタンパク質Trifの変異を特定し,トール型受容体4 (TLR4) 経路から2つの重要なシグナル伝達経路を明らかにした. この発見は,細菌のエンドトキシンとウイルス感染症に対する免疫システムの反応に光を当てています.

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Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity07:09

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