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インタールイキン-1受容体アンタゴニストの欠乏は,怪我後のネオインティマルの形成を促進します

Kikuo Isoda1, Masaru Shiigai, Norio Ishigami

  • 1First Department of Internal Medicine, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama, 359-8513, Japan. isoda@me.ndmc.ac.jp

Circulation
|July 23, 2003
PubMed
まとめ

インタールイキン-1受容体アンタゴニスト (IL-1Ra) の欠如は,マウスの血管損傷後のネオインティマルの形成を著しく増加させます. これは,IL-1Raが動脈硬化などの閉塞性血管疾患に対する保護的役割を果たしていることを示唆しています.

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