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Updated: May 8, 2026

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates
11:28

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

Published on: March 31, 2012

RhoGは,Dock180結合タンパク質"エルモ"との直接相互作用によってRac1を活性化させる

Hironori Katoh1, Manabu Negishi

  • 1Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan. hirokato@pharm.kyoto-u.ac.jp

Nature
|July 25, 2003
PubMed
まとめ

小さなGTPase RhoGは,細胞の拡散とニューライトの成長に不可欠な経路であるElmoとDock180を通ってRac1を活性化します. この発見は,RhoGが細胞形態学とアクチン細胞骨格の調節にどのように影響するかを明らかにしています.

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Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos12:35

Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos

Published on: April 14, 2023

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