関連する実験動画

Updated: Jul 10, 2026

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
16:46

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

Published on: June 3, 2014

クロスブリッジの結合,伸縮への抵抗,および静止している哺乳類の滑らかな筋肉の粘着弾性

M J Siegman, T M Butler, S U Mooers

    Science (New York, N.Y.)
    |January 30, 1976
    PubMed
    まとめ

    休息している哺乳類の滑らかな筋肉は,細胞の脱極化とは無関係に,カルシウムに依存した伸縮抵抗を示します. これは,収縮しない筋肉に付着したクロスブリッジが,このユニークな機械的性質に大きく寄与することを示唆しています.

    さらに関連する動画

    Analysis of Protein-protein Interactions and Co-localization Between Components of Gap, Tight, and Adherens Junctions in Murine Mammary Glands11:31

    Analysis of Protein-protein Interactions and Co-localization Between Components of Gap, Tight, and Adherens Junctions in Murine Mammary Glands

    Published on: May 30, 2017

    Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy08:41

    Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

    Published on: June 13, 2025

    関連する概念動画

    Cell-matrix's Response to Mechanical Forces01:13

    Cell-matrix's Response to Mechanical Forces

    In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
    Anchoring junctions mechanically attach a cell to the...
    Tight Junctions01:29

    Tight Junctions

    Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
    Tension Response at Adherens Junctions01:26

    Tension Response at Adherens Junctions

    The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
    α-Catenin as a Mechanosensory Protein
    The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin homology) domains...
    Dense Connective Tissue01:13

    Dense Connective Tissue

    Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
    Dense Regular Connective Tissue
    In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...
    Fascicle Arrangement in Skeletal Muscles01:25

    Fascicle Arrangement in Skeletal Muscles

    Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
    The four primary types of muscle based on fascicle arrangement are:
    Smooth Muscle Contraction01:25

    Smooth Muscle Contraction

    Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
    The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...