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Updated: Jul 16, 2026

Discovering Protein Interactions and Characterizing Protein Function Using HaloTag Technology
11:16

Discovering Protein Interactions and Characterizing Protein Function Using HaloTag Technology

Published on: July 12, 2014

ヒストンH2BプロモーターのS相活性化は,OCA-Sによって行われ,GAPDHを主要成分として含有するコアクティベーター複合体である

Lei Zheng1, Robert G Roeder, Yan Luo

  • 1Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

Cell
|July 31, 2003
PubMed
まとめ

研究者は,S相依存ヒストンH2B転写に不可欠なタンパク質複合体であるOCA-Sを特定しました. その成分p38は,グリセラルデヒド-3-リン酸脱水素酵素の核形態であり,Oct-1と結合し,転写を細胞サイクル調節と代謝状態とリンクします.

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