公開を超えて:ゲノム情報の公平な利用
1Wellcome Trust Sanger Institute, Hinxton, CB10 1RQ, Cambridge, UK. jes@sanger.ac.uk <jes@sanger.ac.uk>
Lancet (London, England)
|August 9, 2003
まとめ
No abstract available in PubMed .
関連する概念動画
00:49What is Genetic Engineering?
Overview
02:07Organization of Genes
Overview
01:09Recombinant DNA
Overview
03:00Next-generation Sequencing
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
00:53Transgenic Organisms
Overview
01:11Genome-wide Association Studies-GWAS
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...