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Updated: Jul 10, 2026

Potato Virus X-Based microRNA Silencing (VbMS) In Potato.
11:51

Potato Virus X-Based microRNA Silencing (VbMS) In Potato.

Published on: May 11, 2020

マイクロRNAによる葉の形態変異の制御

Javier F Palatnik1, Edwards Allen, Xuelin Wu

  • 1Department of Molecular Biology, Max Planck Institute for Developmental Biology, D-72076 Tübingen, Germany.

Nature
|August 22, 2003
PubMed
まとめ

マイクロRNAは,TCP遺伝子活動を制御することによって,植物の葉の発達を調節する. この研究は,TCPメッセンジャーRNAを分割するマイクロRNAを特定し,異常な葉の成長を防止し,植物種間で保存されたメカニズムを明らかにします.

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Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
MicroRNAs01:22

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
MicroRNAs01:22

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The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the addition of a...