運動と呼吸が全腔肺連結の血流に与える影響:リアルタイム磁気共鳴波動研究
V E Hjortdal1, K Emmertsen, E Stenbøg
1Department of Cardiothoracic and Vascular Surgery, Skejby Hospital, Aarhus University Hospital, DK-8200 Aarhus N, Denmark. vibeke.hjortdal@dadlnet.dk
Circulation
|August 27, 2003
まとめ
下腔静脈 (IVC) と大動脈の血流は,全腔肺連結 (TCPC) の後の患者の運動によって増加します. 呼吸法 呼吸法 呼吸法
科学分野:
- 心臓病学 心臓病学
- 生理学 生理学とは
- メディカルイマージング (医学イメージング)
背景:
- 全腔肺連結 (TCPC) 患者における運動中の血流動力学と呼吸器の影響に関する理解は限られている.
- TCPCは,静脈回路を心臓に変更する手術である.
研究 の 目的:
- TCPC患者における下肢運動を仰向けで行う際に主要な静脈と大動脈の血流の変化を調査する.
- 運動中のTCPC患者における血流に対する呼吸 (吸い込み,吐き出口) の影響を評価する.
主な方法:
- 血液の流れを測定するために,リアルタイム磁気共鳴画像 (MRI) が使用されました.
- 測定は上 vena cava (SVC),下 vena cava (IVC),および上昇性大動脈で行われました.
- 11人のTCPC後の患者は,休息状態および0.5および1.0W/kgのワークロードで運動テストを受けました.
主要な成果:
- 下腔静脈 (IVC) と大動脈の血流は,運動の強度 (P<0.05) が増加するにつれて有意に増加しました.
- 上 vena cava (SVC) の流れは,運動中に変化しませんでした.
- 静止状態では,インスピレーション時のIVCの流れは,エクスパイレーション時の逆流の流れよりも,インスピレーション時のIVCの流れが高く,エクスパイレーション時のIVCの流れは逆流であった. IVCの流れに対するこの呼吸器の影響は,運動によって減少した.
結論:
- TCPC患者の場合,運動はIVCと大動脈の血流を増加させるが,SVCの血流は増加しない.
- インスピレーションによるIVCフローの増加は,休息時に顕著ですが,運動中に顕著ではないので,周辺ポンプがより重要になることを示唆しています.
- TCPC患者では,身体的運動中に心肺呼吸器の相互作用が変化していることが明らかになった.
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