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Updated: Jul 5, 2026

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ヤタケミシン (Yatakemycin) のDNAアルキル化特性について

Jay P Parrish1, David B Kastrinsky, Scott E Wolkenberg

  • 1Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|September 4, 2003
PubMed
まとめ

強力な抗腫瘍化合物であるヤタケミシンは,その生物学的活動のための重要な反応であるDNAアルキル化を受けます. この研究は,選択性および可逆性を含む,そのユニークな"サンドイッチ"アルキル化特性を詳細に説明しています.

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