関連する実験動画

Updated: Jul 19, 2026

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
09:47

Generation of Human Alloantigen-specific T Cells from Peripheral Blood

Published on: November 21, 2014

Tリンパ球の活性化における主要な基因相容性複合体抗原の差異的機能

F H Bach, M L Bach, P M Sondel

    Nature
    |January 29, 1976
    PubMed
    まとめ

    メジャー・ヒストコンパティビリティ・コンプレックス (MHC) は,異なったLDとSD抗原を有し,移植および組織互換性における細胞反応を理解するために重要である. これらの抗原を区別することは,MHCに関連する細胞相互作用に関する将来の実験を設計するのに役立ちます.

    さらに関連する動画

    Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation12:09

    Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

    Published on: February 28, 2019

    Identification of Rare Antigen-Specific T Cells from Mouse Lungs with Peptide:Major Histocompatibility Complex Tetramers09:15

    Identification of Rare Antigen-Specific T Cells from Mouse Lungs with Peptide:Major Histocompatibility Complex Tetramers

    Published on: July 19, 2024

    関連する概念動画

    Cell-mediated Immune Responses01:40

    Cell-mediated Immune Responses

    Overview
    Special Features of Adaptive Immunity01:20

    Special Features of Adaptive Immunity

    The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
    The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
    Antigens Involved in Adaptive Immunity01:26

    Antigens Involved in Adaptive Immunity

    An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
    Complete Antigens
    Complete antigens possess both immunogenicity and reactivity.
    Diversity of Antigen Receptors01:28

    Diversity of Antigen Receptors

    Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
    Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
    T Cell Activation and Clonal Selection01:22

    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
    Naive T cells that have not yet encountered an antigen express two primary CD...
    B Cell Activation and Differentiation01:24

    B Cell Activation and Differentiation

    The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
    When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...