選択的ターゲティングとマトリックスメタルプロテインアース阻害のタイミングは,心筋梗塞後のリモデリングにおける選択的ターゲティングとタイミングです

William M Yarbrough1, Rupak Mukherjee, G Patricia Escobar

  • 1Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, and Procter and Gamble Pharmaceuticals, Mason, Ohio, USA.

Circulation
|September 17, 2003
PubMed
まとめ

選択的マトリックス金属タンパク質酶 (MMP) 阻害により,MMP-1およびMMP-7は保存され,心筋梗塞 (MI) の後の左心室 (LV) の改造に好意的に影響を与えることができます. この選択的なMMP阻害 (sMMPi) のタイミングは,改造パターンに影響を与える.

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