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メジャー・ヒストコンパティビリティ・コンプレックス+ペプチドの溶性T細胞受容体による特定の低親和認識

S Weber1, A Traunecker, F Oliveri

  • 1Basel Institute for Immunology, Switzerland.

Nature
|April 30, 1992
PubMed
まとめ

研究者らは,溶性T細胞受容体 (TCR) を開発し,主要組織適合性複合体の分子によって提示される特定のペプチドと結合した. この生物学的に活性な溶解性TCRは,関連性のあるペプチド抗原と関連性のないペプチド抗原を区別することで,T細胞の活性化を阻害することができます.

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