関連する実験動画

Updated: Jul 12, 2026

Actin Co-Sedimentation Assay; for the Analysis of Protein Binding to F-Actin
07:53

Actin Co-Sedimentation Assay; for the Analysis of Protein Binding to F-Actin

Published on: March 28, 2008

アルファ-アクティニンの機能のためのフォスファディチルイノシトール4,5-ビスホスファートの必要性

K Fukami1, K Furuhashi, M Inagaki

  • 1Department of Biosignal Research, Tokyo Metropolitan Institute of Gerontology, Japan.

Nature
|September 10, 1992
PubMed
まとめ

フォスファディチルイノシトール4,5-ビスホスファート (PtdInsP2) はアルファアクチニンと結合し,アクチン結合およびクロスリンク活性を調節する. この相互作用は,アルファ-アクティニンにとって極めて重要です.

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Measuring Protein Binding to F-actin by Co-sedimentation

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Tuning the Contractility and Deformation Modes of Active Actin-Based Assemblies In Vitro: From Two-Dimensional Active Networks to Liquid Crystal Drops

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関連する概念動画

Amino acids03:42

Amino acids

Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
Introduction to Actin01:26

Introduction to Actin

Actin is a highly conserved cytoskeletal protein found abundantly in eukaryotic cells. It constitutes 10% weight of the total cellular protein in muscle cells, while in non-muscle cells, it is lower and makes up around 1–5 percent of the total cell protein. Actin found in the unicellular amoebae and complex multicellular animals is around 80% similar, demonstrating their conservation over a billion years of evolution.  Actin coding genes are conserved within species and across different species.
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Actin Polymerization

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Generation of Straight or Branched Actin Filaments

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Arp2/3 Complex
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Actin Filament Depolymerization01:19

Actin Filament Depolymerization

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Actin Polymerization and Cell Motility

Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.